Pharmaceutical manufacturer Amhes Pharma has released Freeze Vitamins D-Mannose Cranberry, a fast-absorbing oral spray formulated to support urinary tract health and maintain microbial balance.
The dietary supplement delivers its active ingredients through Amhes Pharma's patented CryoSpray technology, which creates high contact surface area microparticles designed for rapid oral dissolution and enhanced bioavailability.
The product formula combines D-mannose, high-proanthocyanidin cranberry extract, and vitamin C with phospholipids and postbiotics. According to product specifications, the multi-action formulation is designed to protect the urinary epithelium, support bladder health, and promote daily microbial balance through natural defense mechanisms.
Anti-adhesion mechanism and formula components
The primary mechanism of the supplement relies on anti-adhesion action to prevent unwanted microorganisms from attaching to the urinary tract. Amhes Pharma reported that D-mannose binds to pathogenic bacteria such as Escherichia coli, assisting in their natural removal from the urinary tract. Cranberry extract provides proanthocyanidins that reduce the adherence of microorganisms to the bladder epithelium.
Vitamin C is included in the spray to provide antioxidant protection against oxidative stress and support normal immune system function. Phospholipids are incorporated to increase solubility and absorption, while postbiotics are added to maintain microbiome stability and functional body balance.
The urinary system, which comprises the kidneys, bladder, ureters, and urethra, requires continuous biological protection to maintain microbial equilibrium. Bacterial infections in the urinary tract commonly occur when bacteria like E. coli attach to uroepithelial cells. D-mannose is a simple sugar widely recognized in nutritional science for its capacity to prevent bacterial adhesion, while cranberry proanthocyanidins are established plant compounds studied for bladder wall support.
Patented CryoSpray absorption technology
The supplement incorporates Amhes Pharma's proprietary CryoSpray technology, which structures active components into fine microparticles. The manufacturer stated that this technology allows immediate oral dissolution, protecting active ingredients while increasing the likelihood of effective systemic absorption compared to traditional oral dosage forms.
Oral spray delivery systems and liposomal lipid-based carriers are designed to deliver nutrients through the oral mucosa. By utilizing phospholipids to encapsulate active compounds, these systems can improve chemical stability and enhance bioavailability by reducing early degradation in the digestive tract.
Scientific documentation and safety warnings
Amhes Pharma stated that the formulation is supported by published scientific research. Reference literature cited by the manufacturer includes research on vitamin C and immune function published in the EFSA Journal, as well as study findings on cranberry proanthocyanidins and urinary health by A.B. Howell. Additional citations include work by R.G. Jepson on cranberry urinary tract infection prevention, B. Kranjcec on D-mannose applications, and P.C. Calder on lipid-based delivery systems.
The recommended dosage for the supplement is up to seven sprays daily, ideally taken alongside adequate fluid intake. The product label notes that individuals who are pregnant, breastfeeding, or taking prescription medication should consult a healthcare professional before use. The product must be stored in a cool, dry place below 25 degrees Celsius and kept out of reach of children.
As a dietary supplement, the product is not intended to replace a balanced diet or healthy lifestyle. Amhes Pharma confirmed that Freeze Vitamins D-Mannose Cranberry is available directly through the official brand website at www.freezevitamins.com and in retail pharmacies, with manufacturing conducted by Amhes Pharma at www.amhes.com.
